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## Science And Engineering
* __Artificial Intelligence__: [Arcade Learning Environment](https://github.com/mgbellemare/Arcade-Learning-Environment), [ETHNOS](http://ethnos.sourceforge.net/), [Conscious Artificial Intelligence](https://sourceforge.net/projects/cai/), [OpenCog](https://github.com/opencog/opencog), [OpenAI](https://github.com/openai)
* __Astronomy__: [SaVi satellite constellation visualizer](https://sourceforge.net/projects/savi/), Stellarium -> Celestia -> [SkyCat](https://github.com/Starlink/skycat)
* __Bioinformatics__: [UGENE](http://ugene.net/), [OpenSim](https://simtk.org/projects/opensim/), [Cytoscape](http://www.cytoscape.org/), [BioJava](https://github.com/biojava/biojava) -> [EMBOSS](https://github.com/kimrutherford/EMBOSS) -> [SAMtools](https://github.com/samtools/samtools) -> [BioPerl](http://bioperl.org/)
* __Bioinformatics__: [OpenSim](https://simtk.org/projects/opensim/), [Cytoscape](http://www.cytoscape.org/), [BioJava](https://github.com/biojava/biojava) -> [UGENE](http://ugene.net/) -> [EMBOSS](https://github.com/kimrutherford/EMBOSS) -> [SAMtools](https://github.com/samtools/samtools) -> [BioPerl](http://bioperl.org/)
* __CAD__: AutoCAD -> FreeCAD -> [OpenSCAD](https://github.com/openscad/openscad)
* __Chemistry__: [MolComp](http://molcomp.sourceforge.net/), [RasMol](https://directory.fsf.org/wiki/RasMol), [PerlMol](http://www.perlmol.org/)
* __Circuit Simulator__: [ngspice](http://ngspice.sourceforge.net/), [Gnucap](http://www.gnucap.org/dokuwiki/doku.php?id=gnucap:start)